Figure 216-8

Changes in coronary artery vasodilator function in patients with CAD on a 6-month course of fluvastatin. The upper panel shows the MBF at rest and during adenosine hyperemia (A, shaded bars); the lower panel, the pLasma levels for cholesterol in milligrams per deciliter. Note the delayed improvement of hyperemic MBF despite the significant decline in plasma total and LDL cholesterol at 2 months (*p < 0.05 versus baseline).

(Data after Guethlin et aL)